Expression of Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1α Increases After 8-Weeks of Endurance Training in Obese Females

This study aimed to prove the effect of moderate-intensity aerobic exercise on increasing Peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1α) levels in obese women. A total 12 women aged 20-25, with body mass index (BMI) 25-30 kg/m2, normal systolic blood pressure, and resting heart rate as subjects study. Subjects were randomly divided into 2 groups, namely K1 (n=6; control without intervention) K2 exercise). The was carried out an intensity 60% -70% HRmax, frequency 3x/week for 8 weeks. Pretest posttest PGC-1α analyzed using Enzyme-linked immunosorbent assay (ELISA) method. data analysis technique uses Paired Sample T-Test a significant level 5%. Based results it concluded that HRmax weeks affected